Tuesday 2 May 2017

Kit for Paroxysomal Nocturnal Hemoglobinuria (PNH).

An article published this year in “JOURNAL OF THROMBOSIS AND THROMBOLYSIS” using our Kit for Paroxysomal Nocturnal Hemoglobinuria (PNH), by our customers from Hematology Laboratory (Division of Thrombosis and Hemostasis), ICO-Badalona, Hospital Germans Trias i Pujol, Josep Carreras Leukemia Research InstituteUniversitat Autonoma de Barcelona, Badalona, Spain, in the study of Retinal vein occlusion and paroxysmal nocturnal hemoglobinuria. Congrats and Thanks.

Summary:

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder associated with increased risk for thrombosis and reduced life expectancy. Retinal vein occlusion (RVO) is a frequent cause of vision loss but its relationship with PNH has not been studied systematically. Patients followed up for RVO in our ophthalmology department were screened for the presence of a PNH clone in peripheral blood by means of flow cytometry. The presence of other well-documented risk factors for RVO was also analyzed. In a series of 110 patients (54 males, median age of 67) we found no evidence of PNH. Most patients (97/110) had cardiovascular risk factors and/or hyperhomocysteinemia (67/110). Inherited thrombophilias were rare (three confirmed cases). Therefore, PNH does not appear to play a role in the development of RVO. However, this finding does not necessarily apply to young patients and/or those with no conventional risk factors for RVO, due to the low number of patients in these subgroups in our population.

Reference:

Product link:

Kit for Paroxysomal Nocturnal Hemoglobinuria (PNH): http://www.immunostep.com/diagnostic-kits/2335-pnh-kit.html

No comments:

Post a Comment